Rapid igg igm: Omicron strains frequently mutate, what are the effects on vaccines and drugs

Rapid igg igm: Omicron strains frequently mutate, what are the effects on vaccines and drugs

Since South African researchers reported new subtypes BA.4 and BA.5 of the mutated new coronavirus Omicron strain, the United States reported another new subtype of the strain, BA.2.12.1, leading to an increase in infections. Omicron's continuous \"evolution\" is troubling. This strain is frequently mutated. What impact does it have on vaccines and drugs?

Variation frequency

According to the weekly report on the new crown epidemic released by the World Health Organization on April 27, the Ormicron strain is the mainstream variant of the global epidemic. Among the more than 250,000 new coronavirus sequences uploaded to the Global Influenza Shared Database (GISAID) in the past 30 days, 99.7% is Omicron.

Since its emergence in November 2021, the Omicron strain has evolved numerous subtypes and recombinant strains, including early BA.1, BA.2, BA.3, and more recently BA.4, BA.5 and BA.2.12.1, and the recombinant strain XD of the delta strain subtypes AY.4 and BA.1, and the recombinant strain XE of BA.1 and BA.2, and the delta strain and BA.1 The recombinant strain XF. Among them, the BA.2 subtype strain is currently the most prevalent in the world.

Trevor Bedford, a professor in the Division of Vaccines and Infectious Diseases at the Fred Hutchinson Cancer Research Center in the United States, recently released a molecular epidemiological analysis of multiple subtypes of Omicron through social media. He said the study found that BA.2 gradually replaced BA.1 between January and April this year and dominated the global epidemic of new coronavirus strains due to faster transmission.

የኦርሚኒስ አትጨናቂው ለምን እንደዚህ ያሉ ልዩ ልዩ ልዩ ልዩ ልዩ ልዩ ነው? አዲሱን ኮሮኒቫሩስ ከአስተናጋጅ እና ከአካባቢያቸው ጋር ለመላመድ በሚሞክር ሙከራ ውስጥ አዲሱ ኮሮኒቫይስ የተፈጥሮ ምርጫን የመቋቋም ችሎታ እንዳለው ያሳያል.

የኦምሞሮን ውጥረት የፓቶኒካዊነት ክብደት ከዴታ እስክሪፕት የበለጠ ነው, ልዩ \"ጥቅምት \" በዋናነት ዋናው የመዋቢያ ፍሰት እንዲኖር ያደርገዋል. ከፋፊዎች በፊት በክትባቶች ወይም በሌሎች የአዳዲስ ኮሮኒቫይስ የተቋቋሙ ጥናቶች ከቁልፍ ማስተላለፍ ፍጥነት በተጨማሪ ጥናቶች ያሳያሉ.

ሦስቱ አዲስ ብቅ የተደረጉ የኦሚክሮን አተገባበር - b.12.1, B.4 እና BA .5 ጠንካራ የበሽታ የመከላከል ማምረት ችሎታ አላቸው. እ.ኤ.አ. ግንቦት 2 ላይ የፕሮጄክኪንግ ዩኒቨርስቲ የፕሮፌሰር Xieygiang ቡድን ከላይ ያሉት ሦስት አዳዲስ ንዑስ-ነክ አንቀጾችን የሚገታ የባዮዲካል ጠቅላላ ድግግሞሽ በቢዮዲካልኤፍ ኤክስዮሊግስ ውስጥ የታተመ አንድ ጽሑፍን ታትሟል. ጥናቱ ሦስቱም ፍሰቶች የ L452 ሚውቴ በ Spikike ፕሮቲን ላይ ያለው የ L452 ሚውቴሽን እንዳላቸው ተገነዘበ.

L452 ሚውቴሽን እንዲሁ በዴልታ እስክሪፕት ውስጥ ቁልፍ ሚውቴሽን ነው. ቤልፎርድ ከዚህ ቀደም እንደ ባቢ .2 11, እና BA.5 ያሉ ውህዶች ጋር ተንብዮአል. ታዛቢዎች.